Knee pain treatment without surgery can be effectively managed through a variety of non-invasive approaches. Alongside anti-inflammatory medications and physical therapy, patients may benefit from injection therapies such as corticosteroid injections, hyaluronic acid injections, or Platelet-Rich Plasma (PRP) therapy, which help reduce inflammation and promote healing. Additionally, customized knee braces and orthotic devices can provide support and alleviate pressure on the knee joint. Lifestyle modifications, including weight management and low-impact exercises, also play a crucial role in managing knee pain. Alternative treatments like acupuncture and dietary supplements might further complement these approaches for comprehensive relief.